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Do you want to contribute to top quality medical research?

Bioinformatics Scientist to the
FINGERS Brain Health Institute (FBHI)

Are you a Bioinformatics Scientist/Data Scientist with clinical data experience looking for new opportunities? Want to join a team where everyone’s daily work supports activities aimed at preventing Alzheimer’s disease and other forms of dementia?

FBHI drives and coordinates research on risk reduction and prevention of dementia and cognitive decline. Supporting research that builds further on the ground-breaking FINGER study, the institute is a scientific hub for the World-Wide FINGERS network of researchers in more than 65 countries globally, and a driving force in the implementation of scientific findings into clinical, municipal, and public settings.

FBHI consists of a small group of full-time employees and a number of affiliated researchers from several European organizations. We have a particularly close collaboration with Karolinska Institutet and Karolinska University Hospital, both operationally and geographically.

Our work, and the research we support, is funded exclusively by grants, donations, and partnerships.

We are now looking for a Bioinformatics Scientist to our office in Solna, Sweden, for some of our ongoing global collaborative projects, including AD-RIDDLE, an interdisciplinary European initiative working to revolutionize detection, diagnosis, prevention, and treatment of Alzheimer’s disease, and other projects financed by the Alzheimer’s Drug Discovery Foundation, Davos Alzheimer’s Collaborative, and Gates Ventures.

As a Bioinformatics Scientist you will be responsible for planning, coordination, and implementation of data-driven precision medicine projects with related data analyses. You will provide advanced bioinformatics support to scientifically outstanding global research projects in dementia prevention, precision medicine, and diagnostics.

Responsibilities include:
  • Performing advanced data analyses within data-driven projects locally and supporting research teams within the World-Wide FINGERS network in performing analyses of clinical data collected at a national level, with a focus on the use of AD Workbench
  • Developing tools and workflows for such analyses
  • Provisioning of analysis-ready datasets, supported by existing data infrastructures
  • Handling of secure data transfer to enable use of AD Workbench
  • Data processing support – providing data in suitable formats for data exchange and sharing
  • Automation of data/analysis workflows
  • Developing and maintaining FBHI’s bioinformatics platform

The analytical work may, for example, include classification of patients based on molecular profiles and medical record data, to develop methods that enable more informed decisions about treatment. The work may also include support for preclinical research, for example studies in model systems to increase knowledge of disease mechanisms through integrative analysis of multiomics data, microscopy images, and/or dose-response profiles.

Qualifications

We are looking for a driven Bioinformatics Scientist with solid experience of large-scale data analysis in medical research. The applicant needs to meet the following requirements:

  • Doctoral degree in bioinformatics, biomedicine, computer science, or another related field that the employer finds relevant to the position
  • Extensive experience (at least 3 years) of advanced bioinformatics analyses of large-scale data in relation to health outcomes, such as disease risk, survival time, and treatment response, in humans or model systems
  • Experience with biostatistics or machine learning, and knowledge of when it is appropriate to use such methods and their limitations
  • Experience in handling complex data types, data integration, and analytical bioinformatics in the context of multi-omics (proteomics, metabolomics, etc.) and/or clinical data
  • Good ability in one or more programming languages, for instance Python, Rust or R, and good capability to work effectively on large-scale computer clusters
  • Fluency in spoken and written English
  • Skilled in collaborating and communicating with others, while also having ability to run projects independently
  • Eligible to live and work in Sweden, either through citizenship or through residency status at the time of application. Your application will not be considered without this eligibility.
Merits

A doctoral degree is a requirement. Knowledge of clinical trials in precision medicine, translational medical research, health informatics, and biomarker discovery are strong credentials. Skills in integrative analysis of multiomics data, advanced data visualization, and medical image analysis is also strongly meritorious. Great emphasis will be placed on personal suitability and communication skills for work within multidisciplinary and international groups.

Personal characteristics

In order to succeed and thrive in this role, we believe that you are a self-motivated problem solver, with a high level of responsibility and independence and with a structured and quality-conscious way of working. You have good communication skills in both speech and writing. Good collaboration skills and a desire to work in international teams across borders are important.

We will place great emphasis on personal qualities.

What do we offer?

A creative, international, and inspiring environment filled with competence and curiosity.

Employees at FBHI are offered the option of workplace flexibility. This means that if the project you work on allows, you can work part of your working time remotely. You are also offered a yearly wellness reimbursement.

Location: Solna, Sweden

Application

A warm welcome with your application.

The application must include a personal letter describing why you are interested in the position and how it matches your qualifications, as well as a CV that includes a list of your scientific publications if applicable. You can write the application in Swedish or English. Please submit your application via email to careers@fbhi.se no later than November 22, 2024.

For permanent employment, FBHI applies a 6-month probationary period.

If you have questions about the position, please contact us on careers@fbhi.se

FINGERS Brain Health Institute
The FINGERS Brain Health Institute (FBHI) is a non-profit organization founded in 2019. It supports, drives, and coordinates the continued clinical research that builds on the original FINGER study (Ngandu, Kivipelto, et al., Lancet 2015), which showed that multidomain lifestyle factors have significant relevance in the prevention of cognitive decline and dementia.

As a scientific coordinating center for the World-Wide FINGERS network, FBHI supports and connects research teams conducting FINGER-based trials around the world. Since it was established by Professor Miia Kivipelto in 2017, the network has grown to include teams from nearly 70 countries.

FBHI also develops and manages dissemination and implementation activities, to help ensure that scientific findings rapidly come into use in real-world settings, for the benefit of individuals and societies at large.

The FBHI team includes a core team of multidisciplinary experts and specialists, as well as associated researchers from several European institutes. Operationally and geographically, FBHI is particularly close to Karolinska Institutet and the Karolinska University Hospital in Solna, Sweden.

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